Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models

BACKGROUND AND PURPOSE: Blockade of AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors is a good treatment option for a variety of central nervous system disorders. The present study evaluated the neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA rece...

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Detalhes bibliográficos
Main Authors: Gigler, G, Móricz, K, ágoston, M, Simó, A, Albert, M, Benedek, A, Kapus, G, Kertész, S, Vegh, M, Barkóczy, J, Markó, B, Szabó, G, Matucz, É, Gacsályi, I, Lévay, G, Hársing, L G, Szénási, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978282/
https://ncbi.nlm.nih.gov/pubmed/17603549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707362
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