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Tachyphylaxis of the ECL-cell response to PACAP: receptor desensitization and/or depletion of secretory products
BACKGROUND AND PURPOSE: Rat stomach ECL cells secrete histamine and pancreastatin in response to gastrin and pituitary adenylate cyclase-activating peptide-27 (PACAP). This study applies microdialysis to explore how ECL cells in situ respond to PACAP and gastrin. EXPERIMENTAL APPROACH: Both peptides...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1978265/ https://ncbi.nlm.nih.gov/pubmed/17660849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707385 |
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