Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen β receptor

BACKGROUND AND PURPOSE: Angiogenesis is a crucial step in tumour growth and metastasis. Ginsenoside-Rb1 (Rb1), the major active constituent of ginseng, potently inhibits angiogenesis in vivo and in vitro. However, the underlying mechanism remains unknown. We hypothesized that the potent anti-angioge...

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Hlavní autoři: Leung, K W, Cheung, L W T, Pon, Y L, Wong, R N S, Mak, N K, Fan, T-PD, Au, S C L, Tombran-Tink, J, Wong, A S T
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978254/
https://ncbi.nlm.nih.gov/pubmed/17603552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707359
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