Immunization of mice with the nef gene from Human Immunodeficiency Virus type 1: Study of immunological memory and long-term toxicology

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) regulatory protein, Nef, is an attractive vaccine target because it is involved in viral pathogenesis, is expressed early in the viral life cycle and harbors many T and B cell epitopes. Several clinical trials include gene-based vaccines en...

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Bibliographische Detailangaben
Hauptverfasser: Bråve, Andreas, Gudmundsdotter, Lindvi, Gasteiger, Georg, Hallermalm, Kristian, Kastenmuller, Wolfgang, Rollman, Erik, Boberg, Andreas, Engström, Gunnel, Reiland, Sven, Cosma, Antonio, Drexler, Ingo, Hinkula, Jorma, Wahren, Britta, Erfle, Volker
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978202/
https://ncbi.nlm.nih.gov/pubmed/17623060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-9378-2-14
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