Short-term Treatment of RAW264.7 Macrophages with Adiponectin Increases Tumor Necrosis Factor-α (TNF-α) Expression via ERK1/2 Activation and Egr-1 Expression: ROLE OF TNF-α IN ADIPONECTIN-STIMULATED INTERLEUKIN-10 PRODUCTION

Adiponectin is an adipokine with potent anti-inflammatory properties. However, the mechanisms by which adiponectin suppresses macrophage function are not well understood. Treatment of RAW264.7 macrophages with adiponectin for 18 h decreased lipopolysaccharide (LPS)-stimulated tumor necrosis factor-α...

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Hlavní autoři: Park, Pil-hoon, McMullen, Megan R., Huang, Honglian, Thakur, Varsha, Nagy, Laura E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978175/
https://ncbi.nlm.nih.gov/pubmed/17537727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701419200
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