Negative regulation of PI3K by PIK3IP1, a novel p110 interacting protein

Signaling initiated by Class Ia phosphatidylinositol-3-kinases (PI3Ks) is essential for cell proliferation and survival. We discovered a novel protein we call PI3K Interacting Protein 1 (PIK3IP1) that shares homology with the p85 regulatory PI3K subunit. Using a variety of in vitro and cell based as...

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Bibliografiske detaljer
Main Authors: Zhu, Zhenqi, He, Xin, Johnson, Carla, Stoops, John, Eaker, Amanda E., Stoffer, David S., Bell, Aaron, Ph.D., Zarnegar, Reza, DeFrances, Marie C.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978172/
https://ncbi.nlm.nih.gov/pubmed/17475214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.04.096
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