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The Effect of CYP2D6 polymorphisms on the Response to Pain Treatment for Pediatric Sickle Cell Pain Crisis
OBJECTIVES: To test the hypothesis that children taking hydroxyurea who fail codeine therapy would have reduced functioning CYP2D6 alleles. STUDY DESIGN: Children with sickle cell disease presenting to an emergency department with a pain crisis unresponsive to codeine were genotyped. The proportion...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1978168/ https://ncbi.nlm.nih.gov/pubmed/17517247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2007.01.049 |
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