The Effect of CYP2D6 polymorphisms on the Response to Pain Treatment for Pediatric Sickle Cell Pain Crisis

OBJECTIVES: To test the hypothesis that children taking hydroxyurea who fail codeine therapy would have reduced functioning CYP2D6 alleles. STUDY DESIGN: Children with sickle cell disease presenting to an emergency department with a pain crisis unresponsive to codeine were genotyped. The proportion...

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Main Authors: Brousseau, David C, McCarver, D Gail, Drendel, Amy L, Divakaran, Karthika, Panepinto, Julie A
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978168/
https://ncbi.nlm.nih.gov/pubmed/17517247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2007.01.049
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