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Structure of the SARS coronavirus main proteinase as an active C(2) crystallographic dimer

The 34 kDa main proteinase (M(pro)) from the severe acute respiratory syndrome coronavirus (SARS-CoV) plays an important role in the virus life cycle through the specific processing of viral polyproteins. As such, SARS-CoV M(pro) is a key target for the identification of specific inhibitors directed...

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Main Authors: Xu, Ting, Ooi, Amy, Lee, Hooi Chen, Wilmouth, Rupert, Liu, Ding Xiang, Lescar, Julien
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978130/
https://ncbi.nlm.nih.gov/pubmed/16511208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105033257
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