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Generation of predictive pharmacophore model for SARS-coronavirus main proteinase

Pharmacophore-based virtual screening is an effective, inexpensive and fast approach to discovering useful starting points for drug discovery. In this study, we developed a pharmacophore model for the main proteinase of severe acute respiratory syndrome coronavirus (SARS-CoV). Then we used this phar...

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Détails bibliographiques
Publié dans:Eur J Med Chem
Auteurs principaux: Zhang, Xue Wu, Yap, Yee Leng, Altmeyer, Ralf M.
Format: Artigo
Langue:Inglês
Publié: Elsevier SAS. 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115589/
https://ncbi.nlm.nih.gov/pubmed/15642409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2004.09.013
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