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Subunits act independently in a cyclic nucleotide-activated K(+) channel

Ion channels gated by cyclic nucleotides have crucial roles in neuronal excitability and signal transduction of sensory neurons. Here, we studied ligand binding of a cyclic nucleotide-activated K(+) channel from Mesorhizobium loti and its isolated cyclic nucleotide-binding domain. The channel and th...

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Autori principali: Cukkemane, Abhishek, Grüter, Bärbel, Novak, Kerstin, Gensch, Thomas, Bönigk, Wolfgang, Gerharz, Tanja, Kaupp, U Benjamin, Seifert, Reinhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978089/
https://ncbi.nlm.nih.gov/pubmed/17668006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401025
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