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O6-alkylguanine-DNA-alkyltransferase activity and nitrosourea sensitivity in human cancer cell lines.

The DNA repair enzyme, O6-alkylguanine-DNA-alkyltransferase (ATase), is thought to be the principal mechanism controlling resistance to nitrosoureas and related alkylating agents. We compared the sensitivities of five human testis and five bladder tumour cell lines to two nitrosoureas (N-nitroso-N-m...

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Bibliografische gegevens
Hoofdauteurs: Walker, M. C., Masters, J. R., Margison, G. P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1992
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978000/
https://ncbi.nlm.nih.gov/pubmed/1419626
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