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Chlorambucil-monoglutathionyl conjugate is sequestered by human alpha class glutathione S-transferases.

The spontaneous reaction of 110 microM chlorambucil (4-[p-[bis(2-chloroethyl)amino]phenyl]-butanoic acid; CHB) with 5 mM GSH at 37 degrees C in physiological phosphate-buffered saline for 35 min gave primarily the monoglutathionyl derivative, 4-[p-[N-2-chloroethyl,N-2-S-glutathionylethyl]amino]pheny...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Meyer, D. J., Gilmore, K. S., Harris, J. M., Hartley, J. A., Ketterer, B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1992
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977928/
https://ncbi.nlm.nih.gov/pubmed/1520581
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