Cis dichlorodiammine platinum induced DNA interstrand cross-links in primary cultures of human ovarian cancer.

We quantified and examined the kinetics of DNA interstrand cross links (DNA-ISC) caused by Cis dichlorodiammine platinum (DDP) using the method of alkaline elution in 58 highly purified human ovarian tumours growing in primary culture. A large heterogeneity in both the quantity and kinetics of DDP i...

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Autores principales: Balconi, G., Pang, Y., Broggini, M., Morali, F., Marzola, M., Erba, E., Ponti, M., Spinelli, L., Mangioni, C., Redaelli, L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1991
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977530/
https://ncbi.nlm.nih.gov/pubmed/1892757
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