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Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance.

In this report, we investigate several examples of hypoxia-induced drug resistance and compare them with P-glycoprotein associated multidrug resistance (MDR). EMT6/Ro cells exposed to drugs in air immediately after hypoxic treatment developed resistance to adriamycin, 5-fluorouracil, and actinomycin...

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Detalhes bibliográficos
Main Authors: Sakata, K., Kwok, T. T., Murphy, B. J., Laderoute, K. R., Gordon, G. R., Sutherland, R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977469/
https://ncbi.nlm.nih.gov/pubmed/1681885
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