The effect of circulating antigen and radiolabel stability on the biodistribution of an indium labelled antibody.

This study has investigated two of the main problems with radiolabelled antibody imaging, the formation of circulating immune complexes (I.C.) and the non specific binding of radiolabel to the antibody molecule. Patients undergoing immunoscintigraphy with 111In labelled monoclonal antibody ICR2 were...

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Main Authors: Davidson, B. R., Babich, J., Young, H., Waddington, W., Clarke, G., Short, M., Boulos, P., Styles, J., Dean, C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1991
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977445/
https://ncbi.nlm.nih.gov/pubmed/1931605
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