Effective inhibition by low dose aminoglutethimide of peripheral aromatization in postmenopausal breast cancer patients.

Aminoglutethimide without glucocorticoid has been shown to be a clinically effective treatment for postmenopausal breast cancer in low dosage (250 mg day-1). The mechanism of action of this approach is thought to be the inhibition of peripheral aromatase, the enzyme which converts androstenedione to...

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Bibliographic Details
Main Authors: Dowsett, M., Santner, S. J., Santen, R. J., Jeffcoate, S. L., Smith, I. E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977168/
https://ncbi.nlm.nih.gov/pubmed/4015950
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