Observations on the pharmacokinetics of low dose aminoglutethimide in patients with advanced breast cancer.

Serum aminoglutethimide (AG) and N-acetylaminoglutethimide (NAG) concentrations were measured by high pressure liquid chromatography (HPLC) in 24 postmenopausal women with advanced breast cancer receiving increasing doses of oral AG. Patients received 62.5 mg b.d., 125 mg b.d., 250 mg b.d., and 500...

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Main Authors: Stuart-Harris, R., Bradbrook, I., Morrison, P., Smith, I. E., Rogers, H. J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1985
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977148/
https://ncbi.nlm.nih.gov/pubmed/3978028
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