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The "promoting" activity of methyl methanesulphonate in rat bladder carcinogenesis.

The carcinogenic activity of the alkylating agent methyl methanesulphonate (MMS) was investigated in the F344 rat bladder, both untreated and pretreated with a single threshold dose of N-methyl-N-nitrosourea (MNU). On its own, 6 doses of 2.5 mg MMS produced a 7% incidence of bladder cancer. After a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tudor, R. J., Severs, N. J., Hicks, R. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1984
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976922/
https://ncbi.nlm.nih.gov/pubmed/6743515
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