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The "promoting" activity of methyl methanesulphonate in rat bladder carcinogenesis.

The carcinogenic activity of the alkylating agent methyl methanesulphonate (MMS) was investigated in the F344 rat bladder, both untreated and pretreated with a single threshold dose of N-methyl-N-nitrosourea (MNU). On its own, 6 doses of 2.5 mg MMS produced a 7% incidence of bladder cancer. After a...

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Bibliografische gegevens
Hoofdauteurs: Tudor, R. J., Severs, N. J., Hicks, R. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1984
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976922/
https://ncbi.nlm.nih.gov/pubmed/6743515
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