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The "promoting" activity of methyl methanesulphonate in rat bladder carcinogenesis.

The carcinogenic activity of the alkylating agent methyl methanesulphonate (MMS) was investigated in the F344 rat bladder, both untreated and pretreated with a single threshold dose of N-methyl-N-nitrosourea (MNU). On its own, 6 doses of 2.5 mg MMS produced a 7% incidence of bladder cancer. After a...

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Bibliografske podrobnosti
Main Authors: Tudor, R. J., Severs, N. J., Hicks, R. M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1984
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976922/
https://ncbi.nlm.nih.gov/pubmed/6743515
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