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5-fluorouracil and 5-fluoro-2'-deoxyuridine follow different metabolic pathways in the induction of cell lethality in L1210 leukaemia.

The mode of action of 5-fluorouracil (FUra) and 5-fluoro-2'-deoxyuridine (FdUrd) on L1210 leukaemia has been studied. It is shown that FUra and FdUrd follow different routes of metabolism and have different targets with respect to their cytotoxic activity. FUra is converted to 5-fluorouridine-5...

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Bibliografski detalji
Glavni autori: Roobol, C., De Dobbeleer, G. B., Bernheim, J. L.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1984
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976839/
https://ncbi.nlm.nih.gov/pubmed/6234011
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