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Enhancement of melphalan-induced tumour cell killing by misonidazole: an interaction of competing mechanisms.

In the present studies we have used the RIF-1 tumour in C3H mice to try to identify the mechanism(s) responsible for the enhancement of melphalan (L-PAM) induced tumour cell killing by the 2-nitroimidazole misonidazole (MISO). Most of this work was done with a single large dose of MISO (750 mg kg-1)...

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Main Authors: Horsman, M. R., Evans, J. W., Brown, J. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1984
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976784/
https://ncbi.nlm.nih.gov/pubmed/6466544
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