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Local selection rules that can determine specific pathways of DNA unknotting by type II DNA topoisomerases
We performed numerical simulations of DNA chains to understand how local geometry of juxtaposed segments in knotted DNA molecules can guide type II DNA topoisomerases to perform very efficient relaxation of DNA knots. We investigated how the various parameters defining the geometry of inter-segmenta...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1976442/ https://ncbi.nlm.nih.gov/pubmed/17670794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm532 |
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