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Expression of a Myelin Proteolipid Protein (Plp)-lacZ Transgene is Reduced in both the CNS and PNS of Plp(jp) Mice

Jimpy (Plp(jp)) is an X-linked recessive mutation in mice that causes CNS dysmyelination and early death in affected males. It results from a point mutation in the acceptor splice site of myelin proteolipid protein (Plp) exon 5, producing transcripts that are missing exon 5, with a concomitant shift...

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Bibliografski detalji
Glavni autori: Wight, Patricia A., Duchala, Cynthia S., Shick, H. Elizabeth, Gudz, Tatyana I., Macklin, Wendy B.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976413/
https://ncbi.nlm.nih.gov/pubmed/17191136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-006-9202-z
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