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Methotrexate and Erythro-9-(2-hydroxynon-3-yl) Adenine Therapy for Rat Adjuvant Arthritis and the Effect of Methotrexate on In Vivo Purine Metabolism
The objectives were: 1) to test the association of methotrexate (MTX) efficacy in rat adjuvant arthritis (rat AA) with interference of purine biosynthesis and adenosine metabolism and 2) to test the efficacy of erythro-9-(2-hydroxynon-3-yl) adenine (EHNA), an inhibitor of adenosine deaminase, and th...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1976409/ https://ncbi.nlm.nih.gov/pubmed/17408934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2007.02.006 |
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