Negative regulation of the SH(2)-homology–containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoprotein

Expression of SH(2)-homology–containing protein-tyrosine phosphatase-1 (SHP-1), a candidate tumor suppressor, is repressed in human T-cell leukemia virus type-1 (HTLV-1)–transformed lymphocyte cell lines, adult T-cell leukemia (ATL) cells, and in other hematologic malignancies. However, the mechanis...

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Hlavní autoři: Cheng, Jihua, Kydd, Andre R., Nakase, Koichi, Noonan, Kristin M., Murakami, Akikazu, Tao, Hong, Dwyer, Markryan, Xu, Chen, Zhu, Quan, Marasco, Wayne A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2007
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976352/
https://ncbi.nlm.nih.gov/pubmed/17540846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-058388
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