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Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase
Mononuclear phagocyte (macrophages and microglia) dysfunction plays a significant role in the pathogenesis of human immunodeficiency virus (HIV) associated dementia (HAD) through the production and release of soluble neurotoxic factors including glutamate. The mechanism of glutamate regulation by HI...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1976281/ https://ncbi.nlm.nih.gov/pubmed/17596215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.04594.x |
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