T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-γ and IL-13 production

We previously reported that ovalbumin (OVA) and IL-18 nasally administered act on memory type T helper (Th)1 cells to induce airway hyperresponsiveness (AHR) and inflammation, which is characterized by peribronchial infiltration with neutrophils and eosinophils. Here, we report this administration a...

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Hlavní autoři: Hayashi, Nobuki, Yoshimoto, Tomohiro, Izuhara, Kenji, Matsui, Kiyoshi, Tanaka, Toshio, Nakanishi, Kenji
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976243/
https://ncbi.nlm.nih.gov/pubmed/17766435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706378104
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