Renal expression of parvalbumin is critical for NaCl handling and response to diuretics

The distal convoluted tubule (DCT) plays an essential role in the reabsorption of NaCl by the kidney, a process that can be inhibited by thiazide diuretics. Parvalbumin (PV), a Ca(2+)-binding protein that plays a role in muscle fibers and neurons, is selectively expressed in the DCT, where its role...

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Bibliographische Detailangaben
Hauptverfasser: Belge, Hendrica, Gailly, Philippe, Schwaller, Beat, Loffing, Johannes, Debaix, Huguette, Riveira-Munoz, Eva, Beauwens, Renaud, Devogelaer, Jean-Pierre, Hoenderop, Joost G., Bindels, René J., Devuyst, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976223/
https://ncbi.nlm.nih.gov/pubmed/17804801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702810104
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