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Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia
Severe congenital neutropenia (SCN) is an inborn disorder of granulopoiesis. Like most other bone marrow failure syndromes, it is associated with a marked propensity to transform into a myelodysplastic syndrome (MDS) or acute leukemia, with a cumulative rate of transformation to MDS/leukemia that ex...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1975847/ https://ncbi.nlm.nih.gov/pubmed/17494858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-081216 |
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