Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia

Severe congenital neutropenia (SCN) is an inborn disorder of granulopoiesis. Like most other bone marrow failure syndromes, it is associated with a marked propensity to transform into a myelodysplastic syndrome (MDS) or acute leukemia, with a cumulative rate of transformation to MDS/leukemia that ex...

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Detalhes bibliográficos
Main Authors: Link, Daniel C., Kunter, Ghada, Kasai, Yumi, Zhao, Yu, Miner, Tracie, McLellan, Michael D., Ries, Rhonda E., Kapur, Deepak, Nagarajan, Rakesh, Dale, David C., Bolyard, Audrey Anna, Boxer, Laurence A., Welte, Karl, Zeidler, Cornelia, Donadieu, Jean, Bellanné-Chantelot, Christine, Vardiman, James W., Caligiuri, Michael A., Bloomfield, Clara D., DiPersio, John F., Tomasson, Michael H., Graubert, Timothy A., Westervelt, Peter, Watson, Mark, Shannon, William, Baty, Jack, Mardis, Elaine R., Wilson, Richard K., Ley, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975847/
https://ncbi.nlm.nih.gov/pubmed/17494858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-081216
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