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Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts
Tipin and its interacting partner Tim1 (Timeless) form a complex at replication forks that plays an important role in the DNA damage checkpoint response. Here we identify Xenopus laevis Tipin as a substrate for cyclin E/cyclin-dependent kinases 2 that is phosphorylated in interphase and undergoes fu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1975688/ https://ncbi.nlm.nih.gov/pubmed/17846426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706347104 |
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