Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase
Single and multiple mutations at residues 16, 51, 59, 108, and 164 of Plasmodium falciparum dihydrofolate reductase (pfDHFR) have been linked to antifolate resistance in malaria. We prepared and characterized all seven of the pfDHFR mutants found in nature, as well as six mutants not observed in nat...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19755/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037017/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1124 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|