Identification and Validation of Biomarkers of IgV(H) Mutation Status in Chronic Lymphocytic Leukemia Using Microfluidics Quantitative Real-Time Polymerase Chain Reaction Technology

To develop a model incorporating relevant prognostic biomarkers for untreated chronic lymphocytic leukemia patients, we re-analyzed the raw data from four published gene expression profiling studies. We selected 88 candidate biomarkers linked to immunoglobulin heavy-chain variable region gene (IgV(H...

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Bibliographic Details
Main Authors: Abruzzo, Lynne V., Barron, Lynn L., Anderson, Keith, Newman, Rachel J., Wierda, William G., O’Brien, Susan, Ferrajoli, Alessandra, Luthra, Madan, Talwalkar, Sameer, Luthra, Rajyalakshmi, Jones, Dan, Keating, Michael J., Coombes, Kevin R.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2007
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975107/
https://ncbi.nlm.nih.gov/pubmed/17690214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.070001
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