A Two-Gene Signature, SKI and SLAMF1, Predicts Time-to-Treatment in Previously Untreated Patients with Chronic Lymphocytic Leukemia

We developed and validated a two-gene signature that predicts prognosis in previously-untreated chronic lymphocytic leukemia (CLL) patients. Using a 65 sample training set, from a cohort of 131 patients, we identified the best clinical models to predict time-to-treatment (TTT) and overall survival (...

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Autori principali: Schweighofer, Carmen D., Coombes, Kevin R., Barron, Lynn L., Diao, Lixia, Newman, Rachel J., Ferrajoli, Alessandra, O'Brien, Susan, Wierda, William G., Luthra, Rajyalakshmi, Medeiros, L. Jeffrey, Keating, Michael J., Abruzzo, Lynne V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237436/
https://ncbi.nlm.nih.gov/pubmed/22194822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028277
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