DNA Degradation Test Predicts Success in Whole-Genome Amplification from Diverse Clinical Samples

The need to apply modern technologies to analyze DNA from diverse clinical samples often stumbles on suboptimal sample quality. We developed a simple approach to assess DNA fragmentation in minute clinical samples of widely different origin and the likelihood of success of degradation-tolerant whole...

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Detalhes bibliográficos
Main Authors: Wang, Fengfei, Wang, Lilin, Briggs, Christine, Sicinska, Ewa, Gaston, Sandra M., Mamon, Harvey, Kulke, Matthew H., Zamponi, Raffaella, Loda, Massimo, Maher, Elizabeth, Ogino, Shuji, Fuchs, Charles S., Li, Jin, Hader, Carlos, Makrigiorgos, G. Mike
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975106/
https://ncbi.nlm.nih.gov/pubmed/17690213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.070004
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