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Bayesian modelling and ROC analysis to predict placebo responders using clinical score measured in the initial weeks of treatment in depression trials
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: In major depressive disorder an appreciable percentage (40%) of patients in antidepressant trials will have a placebo response. In these trials, early changes (i.e. within the first 4 weeks) of the clinical score scale (e.g. HAMD-17) are associated with resp...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Science Inc
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1974831/ https://ncbi.nlm.nih.gov/pubmed/17488364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02815.x |
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