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Bayesian modelling and ROC analysis to predict placebo responders using clinical score measured in the initial weeks of treatment in depression trials

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: In major depressive disorder an appreciable percentage (40%) of patients in antidepressant trials will have a placebo response. In these trials, early changes (i.e. within the first 4 weeks) of the clinical score scale (e.g. HAMD-17) are associated with resp...

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Detaylı Bibliyografya
Asıl Yazarlar: Gomeni, Roberto, Merlo-Pich, Emilio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974831/
https://ncbi.nlm.nih.gov/pubmed/17488364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02815.x
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