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Receptor-mediated tobacco toxicity: Alterations of the NF-κB expression and activity downstream of α7 nicotinic receptor in oral keratinocytes

To gain a mechanistic insight into nicotinic receptor-dependent morbidity of tobacco products in the oral cavity, we studied effects of exposures of normal human oral keratinocytes (KCs) for 24 h to environmental tobacco smoke (ETS) vs. equivalent concentration of pure nicotine. The exposed KCs show...

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Detalhes bibliográficos
Main Authors: Arredondo, Juan, Chernyavsky, Alexander I., Jolkovsky, David L., Pinkerton, Kent E., Grando, Sergei A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973165/
https://ncbi.nlm.nih.gov/pubmed/17291542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2007.01.013
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