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Upregulation of nuclear factor-κB expression by SLURP-1 is mediated by α(7)-nicotinic acetylcholine receptor and involves both ionic events and activation of protein kinases
SLURP-1 (secreted mammalian Ly-6/urokinase plasminogen activator receptor-related protein-1) is a novel auto/paracrine cholinergic peptide that can bind to α(7)-nicotinic acetylcholine receptor (nAChR), a high Ca(2+)-permeable ion channel coupled to regulation of nuclear factor-κB (NF-κB) expression...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980298/ https://ncbi.nlm.nih.gov/pubmed/20660165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00216.2010 |
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