Upregulation of nuclear factor-κB expression by SLURP-1 is mediated by α(7)-nicotinic acetylcholine receptor and involves both ionic events and activation of protein kinases

SLURP-1 (secreted mammalian Ly-6/urokinase plasminogen activator receptor-related protein-1) is a novel auto/paracrine cholinergic peptide that can bind to α(7)-nicotinic acetylcholine receptor (nAChR), a high Ca(2+)-permeable ion channel coupled to regulation of nuclear factor-κB (NF-κB) expression...

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Detalhes bibliográficos
Main Authors: Chernyavsky, Alexander I., Arredondo, Juan, Galitovskiy, Valentin, Qian, Jing, Grando, Sergei A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Receptors and Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980298/
https://ncbi.nlm.nih.gov/pubmed/20660165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00216.2010
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