Induction of plasminogen activator inhibitor type-1 (PAI-1) by hypoxia and irradiation in human head and neck carcinoma cell lines

BACKGROUND: Squamous cell carcinoma of the head and neck (SCCHN) often contain highly radioresistant hypoxic regions, nonetheless, radiotherapy is a common treatment modality for these tumours. Reoxygenation during fractionated radiotherapy is desired to render these hypoxic tumour regions more radi...

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Detalhes bibliográficos
Main Authors: Schilling, Daniela, Bayer, Christine, Geurts-Moespot, Anneke, Sweep, Fred CGJ, Pruschy, Martin, Mengele, Karin, Sprague, Lisa D, Molls, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973081/
https://ncbi.nlm.nih.gov/pubmed/17663760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-143
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