SR 4233 cytotoxicity and metabolism in DNA repair-competent and repair-deficient cell cultures.

In order to understand in more detail the mechanism underlying the preferential hypoxic cytotoxicity of the benzotriazine N-oxide SR 4233, we have compared the hypoxic cytotoxicity of this drug to the rates of hypoxic metabolism in both DNA double strand break repair-competent and repair-deficient c...

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Bibliographic Details
Main Authors: Biedermann, K. A., Wang, J., Graham, R. P., Brown, J. M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971850/
https://ncbi.nlm.nih.gov/pubmed/2003976
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