Inactivation and clearance of an anti-CEA carboxypeptidase G2 conjugate in blood after localisation in a xenograft model.

Studies with a conjugate of carboxypeptidase G2 (CPG2) and the F(ab')2 fragment of monoclonal anti-CEA antibody, A5B7, have shown specific localisation in a human colon tumour xenograft, LS174T, growing in nude mice. The conjugate reaches a peak concentration in the tumour within 24 h but enzym...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sharma, S. K., Bagshawe, K. D., Burke, P. J., Boden, R. W., Rogers, G. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1990
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971605/
https://ncbi.nlm.nih.gov/pubmed/2337503
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky