IL-1 and IL-4 as reciprocal regulators of IL-2 induced lymphocyte cytotoxicity.

Interleukin 4 (IL-4) suppresses the interleukin 2 (IL-2) induced lymphokine-activated killer (LAK) cell development from human peripheral blood mononuclear cells (PBMC). Suppression is observed at high (1,000 U ml-1) as well as low (10 U ml-1) concentrations of IL-2. IL-4 needs to be present at the...

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Bibliographic Details
Main Authors: Ebina, N., Gallardo, D., Shau, H., Golub, S. H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971504/
https://ncbi.nlm.nih.gov/pubmed/1699593
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