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Evidence that multiple myeloma may be regulated by homeostatic control mechanisms: correlation of changes in the number of clonogenic myeloma cells in vitro with clinical response.

Myeloma colonies (MY-CFUc) could be grown in vitro for 6 months (median time) after a group of 12 myeloma patients had reached complete remission (CR). In a second group of 25 patients MY-CFUc increased in 17/25 and GM-CFUc in 20/25 patients after cyclophosphamide even though 24/25 patients had a pa...

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Autors principals: Maitland, J. A., Millar, B. C., Bell, J. B., Montes, A., Treleaven, J., Gore, M. E., McElwain, T. J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971273/
https://ncbi.nlm.nih.gov/pubmed/2328211
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