Enhanced anti-tumour activity of carmustine (BCNU) with tumour necrosis factor in vitro and in vivo.

The effects on experimental melanoma of a combination of recombinant human tumour necrosis factor alpha (rhTNF alpha) and carmustine (BCNU) were studied in vitro and in vivo. In vitro, BCNU alone was cytotoxic to murine B16 melanoma cells, and at all concentrations of BCNU this toxicity was increase...

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Detalhes bibliográficos
Main Authors: Jones, A. L., Millar, J. L., Millar, B. C., Powell, B., Selby, P., Winkley, A., Lakhani, S., Gore, M. E., McElwain, T. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971510/
https://ncbi.nlm.nih.gov/pubmed/2245169
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