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Activation of CD8(+) T lymphocytes through the T cell receptor turns on CD4 gene expression: Implications for HIV pathogenesis

T cell activation through the T cell receptor is necessary to achieve a specific and effective immune response. We report here that stimulation of CD8(+) T cells through the T cell receptor complex leads to de novo expression of the CD4 antigen on the cell surface that results in susceptibility of C...

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Detalhes bibliográficos
Main Authors: Flamand, Louis, Crowley, Richard W., Lusso, Paolo, Colombini-Hatch, Sandra, Margolis, David M., Gallo, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19703/
https://ncbi.nlm.nih.gov/pubmed/9501224
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