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Higher macrophage inflammatory protein (MIP)-1α and MIP-1β levels from CD8(+) T cells are associated with asymptomatic HIV-1 infection

To test the hypothesis that β-chemokine levels may be relevant to the control of HIV in vivo, we compared RANTES, MIP-1α, and MIP-1β production from purified CD8(+) T cells from 81 HIV-infected subjects and from 28 uninfected donors. Asymptomatic HIV(+) subjects produced significantly higher levels...

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Autors principals: Cocchi, Fiorenza, DeVico, Anthony L., Yarchoan, Robert, Redfield, Robert, Cleghorn, Farley, Blattner, William A., Garzino-Demo, Alfredo, Colombini-Hatch, Sandra, Margolis, David, Gallo, Robert C.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17658/
https://ncbi.nlm.nih.gov/pubmed/11095721
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