The cleaved peptide of the thrombin receptor is a strong platelet agonist
Thrombin cleaves its G-protein-linked seven-transmembrane domain receptor, thereby releasing a 41-aa peptide and generating a new amino terminus that acts as a tethered ligand for the receptor. Peptides corresponding to the new amino terminal end of the proteolyzed seven-transmembrane domain thrombi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9501219/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.6.3082 |
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