Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules
How memory T cells are maintained in vivo is poorly understood. To address this problem, a male-specific peptide (H-Y) was identified and used to activate female anti-H-Y T cells in vitro. Anti-H-Y T cells survived in vivo for at least 70 days in the absence of antigen. This persistence was not beca...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9501216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.6.3065 |
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