The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis

Myelin oligodendrocyte glycoprotein (MOG) is a key CNS-specific autoantigen for primary demyelination in multiple sclerosis. Although the disease-inducing role of MOG has been established, its precise function in the CNS remains obscure. To gain new insights into the physiological and immunopatholog...

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Autori principali: Clements, Craig S., Reid, Hugh H., Beddoe, Travis, Tynan, Fleur E., Perugini, Matthew A., Johns, Terrance G., Bernard, Claude C. A., Rossjohn, Jamie
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC196926/
https://ncbi.nlm.nih.gov/pubmed/12960396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1833158100
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