Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis

Myelin oligodendrocyte glycoprotein (MOG) is an integral membrane protein expressed in CNS oligodendrocytes and outermost myelin lamellae. Anti-MOG Abs cause myelin destruction (demyelination) in animal models of multiple sclerosis (MS); however, such pathogenic Abs have not yet been characterized i...

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Main Authors: Lalive, Patrice H., Menge, Til, Delarasse, Cecile, Della Gaspera, Bruno, Pham-Dinh, Danielle, Villoslada, Pablo, von Büdingen, H.-C., Genain, Claude P.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413723/
https://ncbi.nlm.nih.gov/pubmed/16461459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510672103
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