Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis

Myelin oligodendrocyte glycoprotein (MOG) is an integral membrane protein expressed in CNS oligodendrocytes and outermost myelin lamellae. Anti-MOG Abs cause myelin destruction (demyelination) in animal models of multiple sclerosis (MS); however, such pathogenic Abs have not yet been characterized i...

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Detalhes bibliográficos
Main Authors: Lalive, Patrice H., Menge, Til, Delarasse, Cecile, Della Gaspera, Bruno, Pham-Dinh, Danielle, Villoslada, Pablo, von Büdingen, H.-C., Genain, Claude P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413723/
https://ncbi.nlm.nih.gov/pubmed/16461459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510672103
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